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Oklahoma State Immunization Information System (OSIIS)

The Oklahoma State Immunization Information System (OSIIS) began operations in 1994. It is a statewide immunization registry operated by the Oklahoma State Department of Health. This system is designed to collect and maintain accurate, complete, and current immunization records for Oklahomans of all ages. However, not all clinics participate in OSIIS, therefore OSIIS does not contain the immunization records of all Oklahomans.

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Oklahoma State Immunization Information System (OSIIS)
Training opportunities, information, and updates will be provided once they become available.


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OSIIS Helpdesk

OSIIShelp@health.ok.gov

(405) 271-7200
Monday - Friday
8:30 a.m. to 4:30 p.m.

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