||Contact | A-Z Health Index | Events & Meetings|
Perinatal Hepatitis B Prevention Program (PHBPP)
This site contains HIV prevention messages that might not be appropriate for all audiences. Since HIV infection is spread primarily through sexual practices or by sharing needles, prevention messages and programs on this website may address these topics. If you are not seeking such information or may be offended by such materials, please exit this website.
The OSDH HIV/STD Service provides hepatitis B & C prevention activities, including but not limited to, education, vaccination and Perinatal hepatitis B prevention activities.
Hepatitis means inflammation of the liver. The liver processes nutrients, filters the blood and fights infections. When the liver is inflamed or damaged, how it works can be impacted.
Hepatitis is most often caused by a virus. In the U.S., the most common types of viral hepatitis are Hepatitis A, Hepatitis B and Hepatitis C. Heavy alcohol use, toxins, some medications and certain medical conditions can also cause hepatitis.
What is the Perinatal Hepatitis B Prevention Program (PHBPP)?
The perinatal hepatitis B prevention program (PHBPP) began in 1990 as part of the Vaccine and Immunization Amendments (P.L. 101-502). Congress recognized the need to foster efforts to prevent perinatal hepatitis B virus (HBV) transmission and made resources available to develop and implement programs. The Center for Disease Control and Prevention (CDC) has annually awarded funds which are then provided to awardees such as the State of Oklahoma to support the program.
In 2010, an estimated 24,000 infants were born to hepatitis B surface antigen (HBsAg)-positive women in the United States. When a pregnant woman is infected with the HBV it poses a serious risk that her newborn will contract the infection. Of the infants infected with HBV 90% will develop chronic HBV infection. Twenty-five percent of infants or young children that are chronically infected with the HBV will die prematurely from cirrhosis or liver cancer.
Realizing these statistic and that transmission can be prevented the PHBPP strives to educate healthcare providers and the HBsAg-positive pregnant women on prevention and the importance of treatment.
CDC: 2010 Expected Births point estimate
MMWR December 23. 2005
What are the goals of the PHBPP?
The objectives of the PHBPP are the following:
How to screen a pregnant woman for the hepatitis B virus (HBV)?
The hepatitis B virus (HBV) screening test is called the hepatitis B surface antigen (HBsAg). It detects a protein produced by the virus and can detect a hepatitis B infection even before it causes symptoms. A positive test for a pregnant woman is to be reported to the Oklahoma State Department of Health (OSDH) immediately upon suspicion, diagnosis or positive test. https://www.ok.gov/health/Disease,_Prevention,_Preparedness/Acute_Disease_Service/Disease_Reporting/What_to_Report/index.html
A negative test for the virus means either that there is no current infection or there is not yet a sufficient amount of the antigen to be detected. If a woman participates in high-risk activities that may transmit the HBV (such as unprotected sexual contact or intravenous drug use), retesting later in the pregnancy is generally advised.
How can perinatal hepatitis B transmission be prevented?
Perinatal HBV transmission can be prevented by identifying HBV-infected (i.e., hepatitis B surface antigen [HBsAg]-positive) pregnant women and providing hepatitis B immune globulin (HBIG) and hepatitis B vaccine to their infants within 12 hours of birth. In addition, it is important that the infant completes the hepatitis B vaccine series according to ACIP recommendations and that the post-vaccine serology tests (PVST) are drawn to know if transmission was prevented and the infant has an immunity to the HBV.
The state of Oklahoma requires all birthing hospitals to administer the birth hepatitis B vaccine to all live infants (unless an exemption is completed) within 12 hours of birth and document it in the Oklahoma State Immunization Information System (OSIIS).
What labs to draw to know if transmission of the hepatitis B virus (HBV) was prevented?
Additional Resources: http://www.cdc.gov/hepatitis/HBV/PerinatalXmtn.htm
Test results for all infants born to HBsAg-positive women should be faxed to the Perinatal Hepatitis B Prevention Coordinator at 405-271-5149.
Copyright © State of Oklahoma