Oklahoma Innovations - OCAST's Official Newsletter
2014 Oklahoma Technology Showcase Set for August 28
The 2014 Oklahoma Technology Showcase will be held August 28 at the University of Central Oklahoma in Edmond and will feature nine of the state’s innovative high-tech companies. Showcase presenters will each give a 10 minute presentation that highlights their innovative products or services, life lessons learned as they pursued their ambitions and any needs for collaboration or funding they may have going forward. This year’s event will include guest speakers from Oklahoma’s leading industries and provide ample opportunities to network with inventors, manufacturers, researchers and leaders in the innovation economy.
The Technology Showcase is August 28 from 8:30 a.m. to 5 p.m. at the University of Central Oklahoma’s Nigh University Center.
Sponsorship opportunities and event booth space are still available. Contact Chad Mullen with OCAST at 866-265-2215 or Chad.Mullen@ocast.ok.gov.
OCAST STTR/SBIR Workshops Successful
In mid-February, OCAST hosted three STTR/SBIR workshops in conjunction with OU, OUHSC and OSU. Led by Jim Greenwood of Greenwood Consulting Group, these workshops began with an introduction and overview of the STTR/SBIR program and included information and tips on how to prepare a proposal for a Phase I submission. The day-long workshops were productive and illuminating for the attendees, and Greenwood provided answers to many constructive questions.
If you were unable to attend one of these workshops, OCAST will have two STTR/SBIR webinars in the near future. The dates will be announced in an upcoming newsletter.
SolidTech Receives USDA Award
SolidTech recently received a $100,000 USDA award for its vaccine research to help control Mannheimia haemolytica, the most common cause of Bovine Respiratory Disease, also known as Shipping Fever, in cattle. This type of pneumonia is responsible for wiping out over $500 million worth of cattle every year and is caused by a bacterium that multiplies in the respiratory tract especially following stress caused from shipping, weaning, comingling and viral infections.
Partnering with OSU, SolidTech is developing a vaccine designed to help control outbreaks of Shipping Fever. Starting with research to determine a suitable strain, SolidTech will develop both conventional liquid injectable and dual-dose implantable (SoliDose®) vaccines. The SoliDose vaccine will deliver both primary and booster doses at the same time which will make it more convenient and less costly to protect at-risk cattle. SolidTech will also conduct studies to demonstrate the vaccines are effective, potent, safe and pure.
VADovations Receives Second Fast-Track Award
In 2012, VADovations won a $3 million NIH Fast-Track SBIR award and recently received the Phase I portion of a second Fast-Track for up to $6.75 million. VADovations has developed the world’s smallest implantable blood pump that is smaller, safer and more cost-effective to treat heart failure than current devices. A smaller pump leads to much less invasive surgeries and shorter recovery periods which is better for patients, hospitals and payors. Teaming with Frontier Electronic Systems, VADovations combined their miniature blood pump with Frontier’s nanobattery in order to power the pump, improving the patients’ quality of life.
VADovations intends the SBIR funds for product development, operating costs and pre-clinical studies. Having just completed year one of Phase II of their first Fast-Track SBIR, VADovations reports that their awards represent 20-25% of their funding for development and that they “serve as a great bridge-to-financing as [they] reduce some of the burdens with early-stage technology development.”
Hill Manufacturing Receives SBIR Award
Hill Manufacturing in Tulsa recently received an SBIR grant from the U.S. Department of Agriculture. The grant is the result of a joint proposal effort between Hill Manufacturing, the New Product Development Center (NPDC) at Oklahoma State University, the Oklahoma Manufacturing Alliance (OMA) and the Oklahoma Center for the Advancement of Science and Technology (OCAST).
The NPDC/OMA/OCAST team has been supporting proposal development for small- and medium-sized companies throughout the state as part of a joint economic development effort to increase federal awards to state-based companies. In the development process, the OMA identifies clients with a technology need and guides the client through the proposal process. The NPDC and OCAST bring proposal development expertise to the process and foster research teaming efforts to aid in the development of a successful pitch to the federal government.
For the Hill Manufacturing proposal, Curtis Evans, a Manufacturing Extension Agent for the OMA, introduced Hill Manufacturing to the group and assisted Cheryl Hill and Danny Dunagan of Hill Manufacturing with the process of preparing and submitting the SBIR application. Heather Lewis with the NPDC drove the technical writing process and proposal development and will serve along with several OSU student interns as engineering technical support on the research grant. Chad Mullen with OCAST provided technical and content review support for the effort. The Hill Manufacturing grant will support the development of a series of tree saw devices that are based on a tree cutting attachment that Hill currently offers to the Skid Steer market.
Nanolight Recieves STTR Award
The Nanolight team led by Dr. Zhisheng Shi at the University of Oklahoma recently received a Department of Defense, DARPA STTR Phase I award for their quantum dot mid-IR detectors. The team has received multiple OCAST awards and credits their support with attracting the federal award.
In 2013, OCAST selected Dr. Shi for an Oklahoma Applied Research Support (OARS) award for the “development and commercialization of IV-VI semiconductor mid-infrared detectors.” Mid-infrared (IR) sensing and imaging have widespread military and industrial applications. In 2011, Dr. Shi received an OARS award for “An Integrated Laser Sensor for Medical and Environmental Applications.” The mid-infrared laser sensor is key to success in all mid-infrared gas sensing systems. A light-weight, hand-held sensing system is made possible through an expected breakthrough. Graduate and undergraduate students from OU worked with nano-scale material science, op-electronics processing technology and optical and electrical measurements and sensor applications. The products will be used in homeland security applications and explosive detection and pollution monitoring. Also in 2008, Dr. Shi received OARS funding to research, develop and commercialize new detector structures for infrared detection.
Caisson Biotech Expands Drug Delivery Deal With Novo Nordisk
Caisson Biotech LLC, a biopharmaceutical company with a patented heparosan-based drug delivery technology, HEPtuneTM, announced that it has expanded the scope of its partnership with global healthcare leader Novo Nordisk A/S (NYSE:NVO). This latest license agreement gives Novo Nordisk exclusive rights to commercialize insulin conjugated to HEPtune and non-exclusive rights to leverage the HEPtune technology across other core therapeutic areas including other diabetes care products, human growth hormone therapy, treatments for obesity and for inflammatory diseases, such as Crohn’s, lupus, rheumatoid and psoriatic arthritis.
Under the terms of the agreement, Caisson will be eligible to receive up to $167 million in milestone payments upon achievement of certain predefined clinical, regulatory and commercial objectives plus potential long-term residual royalties.
“Novo Nordisk has completed feasibility studies that pre-clinically validate Caisson’s heparosan-based drug delivery technology for product pharmacokinetics and enhanced half-life,” said Dr. Paul DeAngelis, Chief Scientist of Caisson. “The HEPtune technology uses heparosan, a naturally occurring sugar polymer produced by the body that is stable and inert in the bloodstream while being biodegradable. Furthermore, HEPtune can be customized with respect to polymer size and conjugation chemistry thus providing flexibility to enhance a variety of therapeutic proteins and peptides.”
“As a respected healthcare leader, Novo Nordisk has been an ideal partner and provides the infrastructure and expertise necessary to develop these much-needed therapeutic products,” said Thomas Harlan, CEO of Caisson. “We look forward to our continued collaboration under this new license and to assisting Novo Nordisk in achieving its goal of developing these products and helping more patients.”
About Caisson Biotech LLC
Caisson Biotech, a wholly owned subsidiary of Heparinex LLC, uses novel, heparosan-based conjugates to enhance the therapeutic properties of pharmaceuticals by increasing product half-life, reducing immunogenicity and increasing stability. Chief Scientist and Professor Dr. Paul L. DeAngelis and his team at the University of Oklahoma Health Sciences Center developed this newly invented drug delivery platform. Visit www.caissonbiotech.com.
Caisson is funded and managed by Emergent Technologies Inc. an innovation solutions and technology commercialization leader headquartered in Austin, Texas. Visit www.emergenttechnologies.com.
Oklahoma Unmanned Aerial Systems Summit
The Unmanned Systems Alliance of Oklahoma (USA-OK) hosted the fifth annual Oklahoma Unmanned Aerial Systems (UAS) Summit in Broken Arrow, Oklahoma March 28 on the campus of Northeastern State University (NSU).
“2014 is a pivotal year for the unmanned aerial systems (UAS) industry worldwide and in Oklahoma,” said USA-OK President James L. Grimsley. “For the last few decades, the aerospace industry has represented a significant portion of our state’s economy and the unmanned aerial systems industry is expected to be the most dynamic growth sector within aerospace in the next decade. The UAS industry will be particularly important to Oklahoma because it directly impacts and benefits the biggest segments of our economy, including aerospace, agriculture, defense and energy.”
Oklahoma is committed to fostering economic development and growth for the UAS industry, so in 2011, Oklahoma Governor Mary Fallin created the Governor’s Unmanned Aerial Systems Council. This council is led by the Oklahoma Secretary of Science and Technology and includes representatives from the UAS industry, state government and academia. During the past few years, the council has organized a list of resources and assets including existing statewide collaborations which will be vitally important to the nation as unmanned aerial systems are allowed to safely operate within the national airspace.
The 2014 Summit covered a diverse set of subjects and topics including the use of UAS for agriculture, advanced weather monitoring and research, along with innovative applications for the energy and utility industries and in lifesaving response and situation monitoring during natural or manmade disasters. The summit also included a panel discussion that reviewed the nation’s progress toward achieving safe UAS integration into the national airspace system as mandated by Congress in 2012 and presentations from several national and international UAS and industry experts.
The Unmanned Systems Alliance of Oklahoma (USA-OK) is a state chapter of the Association for Unmanned Vehicle Systems International (AUVSI). More information about USA-OK is at www.usa-ok.org and more information about AUVSI is at www.auvsi.org.
Mullen Promoted to Director of Governmental Relations
Chad Mullen was recently promoted to OCAST Director of Government Relations and Strategic Initiatives. Chad joined the agency on February 4, 2013 as a Programs Officer III. He has an extensive background in statistical research, the development of technical and marketing data for public consumption, data management and data mining and Lean Government initiatives. He holds a Master of Public Administration and a Bachelor of Political Science both from the University of Oklahoma.
In his new role, Chad will serve as a liaison between OCAST and the legislators, lead the organization’s strategic initiatives to ensure continuity across all programs and partner organizations and ensure OCAST is providing services in a complementary and consistent manner.
||OKC Chamber Schmooza Palooza Trade Show
||Webinar: EPA RICE NESHAP Compliance Requirements
|| Intern Partnership Application Deadline
||OARS Application Deadline
||Plant Science Application Deadline
||i2E Innovation Workshop: Before the Business Plan
||Tulsa Chamber Capitol Luncheon
||OU Transnational Cooperation in Space at NASA and ESA
||Tulsa Chamber State of Education
Innovations in History
On April 25, 1961, Robert Noyce was granted a patent for a semi-conductor device-and-lead structure, the integrated circuit otherwise known as the chip. Noyce is credited with being the co-inventor of the integrated circuit along with Jack Kilby.
Advantage Controls in Muskogee offers a complete line of equipment for industrial water treatment professional. They are the industry leader at combining the latest internet communications, electronic control and metering pump innovations into user friendly products for water treatment and control applications. Listen to the Radio Show
Oklahoma’s agriculture is impacted by extremes from drought to sizzling summer temperatures and high winds. The 8th Annual Plasticulture Conference highlighted “Extreme Gardening” featuring Israeli horticultural specialist Itzhak Esquira. Israel is 1/7 the size of Oklahoma and has fewer farmers but produces eight time more produce that our state. Learn more about the advances in technology that are yielding big results. Listen to the Radio Show
Toyota had a challenge with lighting dark spots in their dealership lots. Unable to resolve the issue, they contacted the Department of Energy who referred them to a Native American Company in Anadarko that specializes in LED lights. Learn how the Anadarko manufacturer, Unami, quickly solved the problem and impressed Toyota with their solution.
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Thirty-nine percent of Oklahomans have diabetes, undiagnosed diabetes or are pre-diabetic. Sensulin is developing a true, once-a-day glucose responsive insulin that may mimic a healthy human pancreas. Find out how this innovation could mean a substantial improvement in the lives of those with diabetes, and could give them a chance at a normal life.
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Oklahoma is home to over 552 museums for art, history and natural science among others. Representatives of three of the state’s top museums take listeners on a tour of the Sam Noble Museum of Natural History, Science Museum Oklahoma and the Oklahoma History Center. From dinosaurs to astronauts, the museum exhibits inspire, educate and share the history of our state.
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